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Proteintech
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Salipro Biotech AB
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Image Search Results
Journal: In Vivo
Article Title: FABP7: A Potential Diagnostic and Prognostic Biomarker for Clear Cell Renal Cell Carcinoma
doi: 10.21873/invivo.13773
Figure Lengend Snippet: Expression of FABP7 in clear cell renal cell carcinoma (ccRCC) tissues compared with normal renal and non-ccRCC tissues (20´). A, C, E, G, and I) The illustration depicts histomorphology features with H&E staining of normal renal tissue, ccRCC, papillary RCC (pRCC), chromophobe RCC (chRCC), and rare subtypes RCC (rRCC). B, D, F, H, and J) The expression of FABP7 in normal renal tissue, ccRCC, pRCC, chRCC, and rRCC. B) The weak membranous and cytoplasmic staining of FABP7 in normal renal tubes. D) In ccRCC, FABP7 is expressed differently between low nuclear grade (low expression) and high nuclear grade (high expression). F, H, and J) FABP7 showed negative staining in non-ccRCC groups, including pRCC, chRCC, and rRCC.
Article Snippet: The samples were stained with a
Techniques: Expressing, Staining, Negative Staining
Journal: In Vivo
Article Title: FABP7: A Potential Diagnostic and Prognostic Biomarker for Clear Cell Renal Cell Carcinoma
doi: 10.21873/invivo.13773
Figure Lengend Snippet: The gene distribution and the receiver operating characteristic curve of FABP7 expression between clear cell renal cell carcinoma (ccRCC) and non-ccRCC. A) The box plot diagram of FABP7 protein expression comparing ccRCC and non-ccRCC. The x-axis represents the groups of RCC, and the y-axis represents the gene expression values based on the immunohistology score (H-score). FABP7 increased in ccRCC groups compared with non-ccRCC. B) In the ROC curve and AUC analysis of FABP7 expression, the AUC value was moderate, 0.71. C) The box plots of FABP7 expression in three common subtypes of RCC compared with normal tissues. The x-axis represents the three common subtypes of RCC, including ccRCC, pRCC, and chRCC. The y-axis represents the FABBP7 expression based on log2 values. Expression of FABP7 mRNA in 523 ccRCC compared to 100 normal tissues was statistically significant. In pRCC, there is minimal FABP7 mRNA expression, although lower than that observed in ccRCC. There is no expression of FABP7 mRNA in chRCC. *p<0.05.
Article Snippet: The samples were stained with a
Techniques: Expressing, Gene Expression
Journal: In Vivo
Article Title: FABP7: A Potential Diagnostic and Prognostic Biomarker for Clear Cell Renal Cell Carcinoma
doi: 10.21873/invivo.13773
Figure Lengend Snippet: The violin plots of the correlation between FABP7 and the pathological stage of renal cell carcinoma (RCC) in each subtype. A) ccRCC; the level of FABP7 expression was closely associated with the advanced pathological stages of clear cell RCC (ccRCC). B and C) pRCC and chRCC; the expression of FABP7 was not statistically significant. The x-axis represents the FABP7 expression; the y-axis represents the pathological stages. F Value: F-value is derived from an ANOVA test (Analysis of Variance) and is used to compare the means of the distributions to examined if they are statistically different from each other. An F-value greater than 1 suggests a variability between the group means. Pr(>F): This is the p-value derived from the ANOVA test. A p-value less than 0.05 indicates a statistically significant difference between the group means. The smaller the p-value, the stronger the evidence against the null hypothesis (which would be that there is no difference between the group means). White dot: This indicates the mean of the data.
Article Snippet: The samples were stained with a
Techniques: Expressing, Derivative Assay
Journal: In Vivo
Article Title: FABP7: A Potential Diagnostic and Prognostic Biomarker for Clear Cell Renal Cell Carcinoma
doi: 10.21873/invivo.13773
Figure Lengend Snippet: The result of the Kaplan-Meier analysis of FABP7 expression in clear cell renal cell carcinoma (ccRCC) from the TCGA cohort: A) The overall survival analysis indicated no significant difference between the low and high expression of FABP7 in ccRCC patients; however, there was a trend toward significance [log-rank p=0.086; hazard ratio (HR)=1.3, p(HR)=0.087]. B) The disease-free survival analysis showed that high expression of FABP7 was associated with shortened survival in patients with ccRCC compared to those with low expression [log-rank p=0.008; HR=1.6; p(HR)=0.0087].
Article Snippet: The samples were stained with a
Techniques: Expressing